A group of people with Parkinson’s disease was surveyed and asked what medications they take to treat the disease. If you ever questioned whether this disease is unique in terms of symptoms, just read this list of medications approximately 20 people with Parkinson’s have used or are currently using to treat the symptoms associated with PD. Also, notice the variance of the drugs used to treat depression in PD. Depression is not just a real illness in and of itself, but combined with PD, it can be frightful and very difficult to cope with.
If you are struggling with depression to any degree, let your doctor know right away. It affects every aspect of life.
Drugs used to treat Parkinson’s disease and its symptoms:
- Nuplazid – first drug to treat hallucinations and delusions associated with Parkinson’s disease
- Mertazopine – antidepressant
- Seroquel – It can treat schizophrenia, bipolar disorder, and depression.
- Carbodopa/Levodopa – primarily used to manage the symptoms of Parkinson’s disease but does not change the course of the disease (aka Parcopa and Sinemet)
- Mybetrig – for the treatment of overactive bladder
- Respiridone – (aka Respirdol) It can treat schizophrenia, bipolar disorder, and irritability caused by PD
- Lexapro – antidepressant
- Ativan – used to treat anxiety disorders, trouble sleeping
- Rytary Neuropatch – a combination of carbidopa and levodopa for the treatment of Parkinson’s disease
- Azilect – used as a monotherapy to treat symptoms in early Parkinson’s disease
- Mirapex – treats Parkinson’s disease and restless legs syndrome
- Domperidone – used to relieve nausea and vomiting; to increase the transit of food through the stomach
- Ropinerole – a dopamine agonist, used in the treatment of Parkinson’s disease and restless legs syndrome (RLS)
- Aricept – treats Alzheimer’s disease
- Clonozopin – treats seizures, panic disorder, and anxiety
- Zoloft – antidepressant
- Endacapone – used to treat PD
- Stalevo – three medicines – levodopa, carbidopa and entacapone. They work together to increase the levels of dopamine in the brain. Used to treat Parkinson’s disease
- Amantadine – treats Parkinson’s disease and parkinson-like symptoms caused by certain medications
- Linzess – used as a laxative
- Alprazalam – used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety
- Gabepentin – Nerve pain medication; restless leg syndrome; chronic pain;
- Oxycodone – treats moderate to severe pain
- Exelon patch – can treat dementia
- Cymbalta – It can treat depression, anxiety, diabetic, and chronic muscle or bone pain
- Magnesium – Magnesium is a mineral that acts as a natural relaxant. Some indications of deficiency are: muscle tremors or spasm, muscle weakness, insomnia or nervousness, high blood pressure, irregular heartbeat, constipation, hyperactivity, depression. Magnesium’s role in supporting good sleep may also be quite important here, since many people with Parkinson’s experience poor sleep patterns.
- Vitamin B12 – Researchers concluded that low B12 status may be a risk factor for greater morbidity in Parkinson’s, and efforts to prevent or correct the deficiency should be undertaken to possibly slow the onset of disability in Parkinson’s disease. (Christine C et al. Abstract S411. Presented at: American Neurological Association Annual Meeting 2015. September 27-29, 2015; Chicago.)
- Vitamin D – Researchers report that there is a correlation between insufficient levels of vitamin D and the development of early Parkinson’s disease.
- Omega 3 – The omega-3’s are anti-inflammatory which may be beneficial as neuro-inflammation is a feature of Parkinson’s. Mood problems are also a common feature and there has been a lot of research into the mood-boosting properties of the omega-3 essential fats. A small placebo-controlled pilot trial reported significantly greater improvement of depression in Parkinson’s patients treated with omega-3 fatty-acid supplementation versus placebo. The richest dietary source is from fish such as salmon, mackerel, herring, sardines, trout, pilchards and anchovies.